Remote Insensitivity is an online recreation of the popular game Cards Against Humanity for up to 6 players. BE WARNED: this game is not for the faint of heart and can get embarrassing! It should probably not be played in mixed company! Rather than reinvent the wheel, I will share this instructional video from Youtube:
UPDATE: This seems to have been taken down. I e-mailed the people at Cards Against Humanity and they recommended this site. I haven't had a chance to really try it out yet, but it looks like it can work with a little more of a learning curve.